Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

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*Currency in USD

Company Revenue

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Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

,

cholesterol ester storage disease

,

,

failure to thrive

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

end stage liver disease

,

,

atypical hemolytic uremic syndrome

,

,

kidney transplantation

,

kidney diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

,

complement activation

,

psychology rejection

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

macular degeneration

,

geographic atrophy

,

,

,

hemolytic-uremic syndrome

,

myasthenia gravis

,

neuromyelitis optica

,

muscle weakness

,

delayed graft function

,

guillain-barre syndrome

,

left ventricular dysfunction

,

ventricular dysfunction

,

escherichia coli infections

,

shiga-toxigenic escherichia coli

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

respiratory distress syndrome

,

,

acute lung injury

,

hypophosphatasia

,

severe acute respiratory syndrome

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

disease progression

,

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

geographic atrophy

,

paroxysmal hemoglobinuria

,

,

,

Mycophenolate sodium

lupus nephritis

,

,

multiple sclerosis

atopic dermatitis

,

,

,

type 2 diabetes mellitus

,

healthy volunteers/patients

,

,

pulmonary tuberculosis

,

,

diabetes mellitus

,

insulin resistance

,

b-cell chronic lymphocytic leukemia

,

hodgkin disease

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

bronchiolitis obliterans syndrome

,

t-cell lymphoma

,

follicular lymphoma

,

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

,

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

Choline alfoscerate

,

,

coronary disease

,

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

biphenotypic leukemia acute

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

endometrial neoplasms

,

uterine cervical neoplasms

,

,

myeloid leukemia acute

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

mantle-cell lymphoma

,

ovarian neoplasms

,

aids-related lymphoma

,

central nervous system neoplasms

,

,

rheumatoid arthritis

,

,

,

,

stem cell transplantation

,

systemic scleroderma

,

,

interstitial lung diseases

,

localized scleroderma

,

diffuse scleroderma

,

behcet syndrome

,

neoplasm metastasis

,

residual neoplasm

,

reactive arthritis

,

immunoblastic lymphadenopathy

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

triple negative breast neoplasms

,

inflammatory breast neoplasms

,

lupus nephritis

,

,

colorectal neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

patient preference

,

membranous glomerulonephritis

,

systemic lupus erythematosus

,

breast neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

follicular lymphoma

,

,

postmenopausal osteoporosis

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