Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Marketed Drugs

Clinical Trials

Financial

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Company Revenue

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Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

mucopolysaccharidosis iv

,

mucopolysaccharidosis vi

,

glycogen storage disease type ii

,

sudden infant death

,

mucopolysaccharidosis vii

,

gaucher disease

,

,

cholesterol ester storage disease

,

,

failure to thrive

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

end stage liver disease

,

,

atypical hemolytic uremic syndrome

,

,

kidney transplantation

,

kidney diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

,

complement activation

,

psychology rejection

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

macular degeneration

,

geographic atrophy

,

,

,

hemolytic-uremic syndrome

,

myasthenia gravis

,

neuromyelitis optica

,

muscle weakness

,

delayed graft function

,

guillain-barre syndrome

,

left ventricular dysfunction

,

ventricular dysfunction

,

escherichia coli infections

,

shiga-toxigenic escherichia coli

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

respiratory distress syndrome

,

,

acute lung injury

,

hypophosphatasia

,

severe acute respiratory syndrome

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

disease progression

,

healthy volunteers/patients

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

geographic atrophy

,

paroxysmal hemoglobinuria

,

,

,

Mycophenolate sodium

healthy volunteers/patients

healthy volunteers/patients

,

type 2 diabetes mellitus

,

,

,

,

non-small-cell lung carcinoma

,

,

respiratory syncytial virus infections

,

brain neoplasms

,

central nervous system neoplasms

,

,

glucose metabolism disorders

,

metabolic diseases

,

alzheimer disease

,

huntington disease

,

thyroid neoplasms

,

,

sickle cell anemia

,

atopic dermatitis

,

,

colorectal neoplasms

,

anxiety disorders

,

prostatic neoplasms

,

breast neoplasms

,

,

adenocarcinoma of lung

,

generalized anxiety disorder

,

reflex epilepsy

,

bipolar disorder

,

diabetes mellitus

,

,

status epilepticus

,

critical illness

,

,

psychomotor agitation

,

post-traumatic stress disorders

,

executive function

,

,

partial epilepsies

,

generalized epilepsy

,

complex partial epilepsy

,

,

insulin resistance

,

metabolic syndrome

,

,

major depressive disorder

,

depressive disorder

,

psychotic disorders

,

gastrointestinal endoscopy

,

hyperlipidemias

,

,

waldenstrom macroglobulinemia

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

non-hodgkin lymphoma

b-cell chronic lymphocytic leukemia

,

,

hodgkin disease

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

bronchiolitis obliterans syndrome

,

,

t-cell lymphoma

,

follicular lymphoma

,

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

,

non-hodgkin lymphoma

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

hepatitis b virus

,

chronic hepatitis b

,

,

,

Choline alfoscerate

,

,

coronary disease

,

,

lymphoid leukemia

,

squamous cell carcinoma

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

interdigitating dendritic cell sarcoma

,

squamous cell neoplasms

,

adenosquamous carcinoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

philadelphia chromosome

,

myelodysplastic syndromes

,

graft vs host disease

,

gata2 deficiency

,

neoplasm metastasis

,

small cell carcinoma

,

neuroendocrine carcinoma

,

squamous cell carcinoma of head and neck

,

mouth neoplasms

,

gastrointestinal neoplasms

,

adenoviridae infections

,

,

,

,

,

,

pancreatic neoplasms

,

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

ovarian neoplasms

,

non-small-cell lung carcinoma

,

,

serous cystadenocarcinoma

,

b-cell lymphoma

,

colorectal neoplasms

,

myeloid leukemia acute

,

prostatic neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

hematologic neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

cholangiocarcinoma

,

malignant mesothelioma

,

,

,

pancreatic ductal carcinoma

,

ovarian epithelial carcinoma

,

,

triple negative breast neoplasms

,

myeloid leukemia

,

head and neck neoplasms

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

breast neoplasms

,

multiple myeloma

,

plasma cell neoplasms

1

2

3

4

5

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