Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

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*Currency in USD

Company Revenue

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Quarterly

Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Myasthenia gravis , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

mucopolysaccharidosis iv

,

glycogen storage disease type ii

,

lysosomal storage diseases

,

gaucher disease

,

,

cholesterol ester storage disease

,

,

failure to thrive

healthy volunteers/patients

,

,

end stage liver disease

,

kidney diseases

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

,

chronic kidney failure

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

,

multiple organ failure

,

diabetes mellitus

,

thrombocytopenia

,

complement activation

,

renal insufficiency

,

wounds and injuries

,

reperfusion injury

,

chronic renal insufficiency

,

hemolytic anemia autoimmune

,

,

antiphospholipid syndrome

,

macular degeneration

,

geographic atrophy

,

,

dermatomyositis

,

autoimmune diseases

,

neuromyelitis optica

,

myasthenia gravis

,

kidney transplantation

,

muscle weakness

,

vascular diseases

,

thrombotic microangiopathies

,

guillain-barre syndrome

,

delayed graft function

,

escherichia coli infections

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

shiga-toxigenic escherichia coli

,

,

,

malignant hypertension

,

hypertensive crisis

,

phenylketonurias

,

paroxysmal hemoglobinuria

,

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

,

coronavirus infections

,

hypophosphatasia

,

respiratory distress syndrome

,

,

acute lung injury

,

viral pneumonia

,

,

newborn respiratory distress syndrome

,

,

protein-losing enteropathies

,

intestinal diseases

,

,

lymphangiectasis

,

intestinal lymphangiectasis

,

,

disease progression

,

intestinal obstruction

,

,

allergic fungal sinusitis

,

,

healthy volunteers/patients

,

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

macular degeneration

,

geographic atrophy

,

,

paroxysmal hemoglobinuria

,

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

,

t-cell lymphoma

,

hodgkin disease

,

follicular lymphoma

,

b-cell lymphoma

,

lymphoid leukemia

,

myeloid leukemia acute

,

,

myeloid leukemia

,

breast neoplasms

,

ovarian neoplasms

,

triple negative breast neoplasms

,

fallopian tube neoplasms

,

male breast neoplasms

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

Choline alfoscerate

,

esophageal neoplasms

,

neoplasm metastasis

,

hepatocellular carcinoma

,

liver neoplasms

,

healthy volunteers/patients

,

,

multiple myeloma

,

,

squamous cell carcinoma

,

plasma cell neoplasms

,

colorectal neoplasms

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

rectal neoplasms

,

non-hodgkin lymphoma

,

,

synovial sarcoma

,

,

,

sezary syndrome

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

urologic neoplasms

,

urogenital neoplasms

,

penile neoplasms

,

male urogenital diseases

,

urogenital diseases

,

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

,

,

urinary bladder neoplasms

,

triple negative breast neoplasms

,

giant cell arteritis

,

polymyalgia rheumatica

,

ulcerative colitis

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

rheumatoid arthritis

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

uterine cervical neoplasms

,

,

cardiovascular diseases

,

hyperlipidemias

,

familial combined hyperlipidemia

,

hyperlipoproteinemias

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

immunoglobulin light-chain amyloidosis

,

,

paraproteinemias

1

2

3

4

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