Alexion Pharmaceuticals - PharmaKB

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Company ReportsAlexion Pharmaceuticals

Alexion Pharmaceuticals(ALXN)

Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.

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Financial

Marketed Drugs

Clinical Trials

Financial

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*Currency in USD

Company Revenue

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Annual

Annual

Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

All

Classification:

All

Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kanuma	Sebelipase alfa	2015-12-08		Inborn errors lipid metabolism
Soliris	Eculizumab	2007-03-16		Paroxysmal hemoglobinuria , Atypical hemolytic uremic syndrome
Strensiq	Asfotase alfa	2015-10-23		Hypophosphatasia
Ultomiris	Ravulizumab	2018-12-21		Paroxysmal hemoglobinuria, Atypical hemolytic uremic syndrome

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypophosphatasia

Sebelipase alfa

mucopolysaccharidosis iv

,

glycogen storage disease type ii

,

gaucher disease

,

,

cholesterol ester storage disease

,

,

failure to thrive

healthy volunteers/patients

,

paroxysmal hemoglobinuria

,

healthy volunteers/patients

,

,

hepatic insufficiency

,

renal insufficiency

,

glomerulonephritis

,

membranoproliferative glomerulonephritis

,

,

macular degeneration

,

geographic atrophy

,

,

paroxysmal hemoglobinuria

,

,

Mycophenolate sodium

hyperlipoproteinemia type i

Calcium carbonate

renal insufficiency

,

hyperphosphatemia

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

healthy volunteers/patients

,

head and neck neoplasms

,

precancerous conditions

,

pancreatic neoplasms

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

hypersensitivity

,

,

chronic renal insufficiency

,

kidney diseases

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

,

hodgkin disease

,

b-cell lymphoma

,

lymphoid leukemia

,

,

,

t-cell lymphoma

,

follicular lymphoma

,

large-cell lymphoma anaplastic

,

t-cell lymphoma peripheral

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia

myocardial infarction

,

,

inferior wall myocardial infarction

,

coronary artery disease

,

cardiopulmonary bypass

,

coronary artery bypass

Choline alfoscerate

healthy volunteers/patients

,

cardiovascular diseases

,

,

,

child development

,

,

male infertility

,

,

esophageal neoplasms

,

,

non-hodgkin lymphoma

,

,

hodgkin disease

,

large b-cell lymphoma diffuse

,

food diet and nutrition

,

lymphangioleiomyomatosis

,

,

,

pharmacokinetics

,

,

hepatocellular carcinoma

,

liver neoplasms

,

fetal alcohol spectrum disorders

,

cystic fibrosis

,

breast neoplasms

,

,

,

,

triple negative breast neoplasms

,

substance-related disorders

,

cognition disorders

,

neurodevelopmental disorders

,

marijuana abuse

,

heart valve diseases

,

,

,

myeloid leukemia acute

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

myeloid leukemia

,

erythroblastic leukemia acute

,

hypersensitivity

,

,

,

reperfusion injury

,

myocardial reperfusion injury

,

,

,

exocrine pancreatic insufficiency

,

,

,

cerebellar ataxia

,

,

prostatic neoplasms

,

,

,

hypertriglyceridemia

,

,

non-alcoholic fatty liver disease

,

hyperparathyroidism

,

,

prader-willi syndrome

,

hepatolenticular degeneration

,

coronary artery disease

,

premature birth

,

,

ischemic stroke

,

open-angle glaucoma

,

,

primary hyperparathyroidism

,

coronary disease

,

myocardial ischemia

,

metabolic syndrome

,

,

,

parathyroid neoplasms

,

diabetic neuropathies

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

brain hypoxia-ischemia

,

castration-resistant prostatic neoplasms

,

parathyroid diseases

,

rapid sequence induction and intubation

,

hyperhomocysteinemia

,

liver cirrhosis

,

atherosclerotic plaque

,

,

,

iron-deficiency anemia

,

iron deficiencies

,

neuroprotection

,

cognitive dysfunction

,

alzheimer disease

,

,

,

,

,

,

,

cerebral infarction

,

,

diabetes mellitus

,

,

,

wounds and injuries

,

traumatic brain injuries

,

,

optic nerve diseases

,

,

,

,

atherosclerosis

,

bipolar disorder

,

peripheral nervous system diseases

,

ischemic optic neuropathy

,

,

myocardial infarction

,

cocaine-related disorders

,

,

type 2 diabetes mellitus

,

alcohol drinking

,

microvascular angina

,

chemical and drug induced liver injury

,

asperger syndrome

,

,

autistic disorder

,

psychotic disorders

,

,

,

,

alcoholic hepatitis

,

postoperative pain

,

neural conduction

,

carotid artery diseases

,

respiratory aspiration

,

,

,

,

heart disease risk factors

,

,

depressive disorder

,

brain neoplasms

,

neoplasm metastasis

,

,

,

,

neuroendocrine carcinoma

,

thyroid diseases

,

muscle weakness

,

major depressive disorder

,

choline deficiency

,

anxiety disorders

,

,

,

prostatic hyperplasia

,

,

,

,

body weight changes

,

,

,

non-small-cell lung carcinoma

,

infant nutrition disorders

,

alcoholic liver diseases

,

,

thyroid neoplasms

,

papillary thyroid cancer

,

coronary stenosis

,

,

bone marrow diseases

,

,

erdheim-chester disease

,

,

langerhans-cell histiocytosis

,

tourette syndrome

,

myasthenia gravis

,

amphetamine-related disorders

,

,

,

liver transplantation

,

,

gestational diabetes

,

,

,

neurodegenerative diseases

,

,

,

carotid stenosis

,

irritable bowel syndrome

,

positron-emission tomography

,

total parenteral nutrition

,

endometrial neoplasms

,

uterine cervical neoplasms

,

,

lymphatic metastasis

,

muscle strength

,

,

uveal neoplasms

,

urologic neoplasms

,

amyotrophic lateral sclerosis

,

muscle spasticity

,

motor neuron disease

,

hereditary spastic paraplegia

,

,

,

intestinal failure

,

postpartum depression

,

,

hypercholesterolemia

,

,

,

communicable diseases

,

,

essential hypertension

,

,

,

,

neurotoxicity syndromes

,

peripheral nerve injuries

,

nerve degeneration

,

organophosphate poisoning

,

neuroinflammatory diseases

,

obstetrical anesthesia

,

emotional regulation

,

executive function

,

cold temperature

,

gastrointestinal diseases

,

digestive system diseases

,

,

severe acute malnutrition

,

neuroendocrine tumors

,

,

,

exercise tolerance

,

therapeutic chemoembolization

1

2

3

4

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