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Alexion Pharmaceuticals
Alexion Pharmaceuticals
(ALXN)
Alexion Pharmaceuticals is an American pharmaceutical company headquartered in Boston, Massachusetts that specializes in orphan drugs to treat rare diseases. It became an independent subsidiary of AstraZeneca in 2021.
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Revenue by Drug
Marketed Drugs
Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Kanuma
Sebelipase alfa
2015-12-08
Inborn errors lipid metabolism
Soliris
Eculizumab
2007-03-16
Paroxysmal hemoglobinuria
,
Myasthenia gravis
,
Atypical hemolytic uremic syndrome
Strensiq
Asfotase alfa
2015-10-23
Hypophosphatasia
Ultomiris
Ravulizumab
2018-12-21
Paroxysmal hemoglobinuria
,
Atypical hemolytic uremic syndrome
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Ravulizumab
healthy volunteers/patients
,
glomerulonephritis
,
lupus nephritis
,
pre-eclampsia
,
hemolysis
,
thrombotic microangiopathies
,
neuromyelitis optica
,
iga glomerulonephritis
,
syndrome
,
anemia
,
vascular diseases
,
hemolytic-uremic syndrome
,
azotemia
,
chronic renal insufficiency
,
proteinuria
,
acute kidney injury
,
respiratory distress syndrome
,
pneumonia
,
acute lung injury
,
viral pneumonia
,
lung injury
,
newborn respiratory distress syndrome
,
amyotrophic lateral sclerosis
,
motor neuron disease
,
sclerosis
,
recurrence
,
transverse myelitis
,
demyelinating diseases
,
optic neuritis
,
muscle weakness
,
dermatomyositis
,
cardiopulmonary bypass
,
heart diseases
,
kidney transplantation
,
delayed graft function
,
iga vasculitis
,
vasculitis
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
myasthenia gravis
,
atypical hemolytic uremic syndrome
,
covid-19
,
adrenal insufficiency
,
pregnancy
Asfotase alfa
hypophosphatasia
Sebelipase alfa
fabry disease
,
cholesterol ester storage disease
,
wolman disease
,
failure to thrive
Eculizumab
healthy volunteers/patients
,
paroxysmal hemoglobinuria
,
hemoglobinuria
Danicopan
healthy volunteers/patients
,
hepatic insufficiency
,
renal insufficiency
,
glomerulonephritis
,
membranoproliferative glomerulonephritis
,
covid-19
,
geographic atrophy
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
hemolysis
,
anemia
Mycophenolate sodium
neoplasms
,
recurrence
,
precursor cell lymphoblastic leukemia-lymphoma
,
hematologic neoplasms
,
liver transplantation
,
myelodysplastic syndromes
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
hodgkin disease
,
lymphoma
,
heart transplantation
,
multiple myeloma
,
bcr-abl positive chronic myelogenous leukemia
,
graft vs host disease
,
liver diseases
,
renal insufficiency
,
aplastic anemia
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
diabetic nephropathies
,
type 1 diabetes mellitus
,
kidney transplantation
,
graft rejection
,
chronic kidney failure
,
psychology rejection
,
kidney diseases
,
cytomegalovirus
,
transplantation
,
diabetes mellitus
,
atopic dermatitis
Benzodiazepine
healthy volunteers/patients
,
psoriasis
,
hepatitis c
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
psoriatic arthritis
,
neoplasms
,
obesity
,
overweight
,
sleep initiation and maintenance disorders
,
hiv infections
,
liver cirrhosis
Benzimidazole
healthy volunteers/patients
,
inflammatory bowel diseases
,
intestinal diseases
,
rheumatoid arthritis
,
arthritis
,
osteoarthritis
Cerdulatinib
vitiligo
Pexelizumab
myocardial infarction
,
infarction
,
inferior wall myocardial infarction
,
coronary artery disease
,
cardiopulmonary bypass
,
coronary artery bypass
Tenofovir
tuberculosis
Choline alfoscerate
alzheimer disease
Somatostatin
neuroendocrine tumors
Doconexent
healthy volunteers/patients
,
hiv
,
b-cell chronic lymphocytic leukemia
,
obesity
,
overweight
,
immunoglobulin light-chain amyloidosis
,
syndrome
,
lymphoid leukemia
,
residual neoplasm
,
myelodysplastic syndromes
,
preleukemia
,
depression
,
treatment-resistant depressive disorder
,
depressive disorder
,
crohn disease
,
recurrence
,
poems syndrome
,
alzheimer disease
,
frailty
,
leukemia
,
neoplasms
,
precursor cell lymphoblastic leukemia-lymphoma
,
paraproteinemias
,
lymphoma
,
follicular lymphoma
,
amyloidosis
,
smoldering multiple myeloma
,
rheumatoid arthritis
,
arthritis
,
multiple myeloma
,
plasma cell neoplasms
Lornoxicam
aggression
,
multiple sclerosis
,
myeloid leukemia acute
,
large b-cell lymphoma diffuse
,
osteosarcoma
,
benign fibrous histiocytoma
,
histiocytoma
,
malignant fibrous histiocytoma
,
reactive arthritis
,
brain neoplasms
,
medulloblastoma
,
primitive neuroectodermal tumors
,
infratentorial neoplasms
,
ovarian neoplasms
,
neoplasms
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
sarcoma
,
neuroblastoma
,
ewing sarcoma
,
breast neoplasms
,
lymphoma
,
b-cell lymphoma
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
leukemia
,
lymphoid leukemia
,
follicular lymphoma
,
lupus nephritis
,
systemic lupus erythematosus
,
triple negative breast neoplasms
,
thrombocytopenic purpura idiopathic
,
thrombocytopenic purpura
,
purpura
,
nephritis
,
hemophilia a
,
vasculitis
,
granulomatosis with polyangiitis
,
microscopic polyangiitis
,
systemic vasculitis
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